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New Technologies in Radiation Oncology
25 January 2011

New Technologies in Radiation Oncology
New Technologies in Radiation Oncology (Medical Radiology / Radiation Oncology)
Publisher: Springer | 2006 | ISBN: 3540003215 | Pages: 464 | PDF | 15,84 MB

This book provides an overview of recent advances in radiation oncology, many of which have originated from physics and engineering sciences. After an introductory section on basic aspects of 3D medical imaging, the role of 3D imaging in the context of radiotherapy is explored in a series of chapters on the various modern imaging techniques. A further major section addresses 3D treatment planning for conformal radiotherapy, with consideration of both external radiotherapy and brachytherapy. Subsequently the modern techniques of 3D conformal radiotherapy are described, including stereotactic radiotherapy, intensity-modulated radiation therapy, image-guided and adaptive radiotherapy, and radiotherapy with charged particles. More clinically oriented chapters explore the use of brachytherapy in patients with prostate cancer, cardiovascular disorders and breast cancer. The book concludes with sections on patient positioning and quality assurance. The text is specifically designed to be accessible to professionals and students with a medical background as well as to newcomers to radiation oncology from the field of physics.

Principles and Practice of Clinical Research
16 January 2011

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research

2002 | 490 | ISBN: 0122740653 | PDF | 42 Mb

This timely book on how to conduct, evaluate, and monitor clinical research was written by leading experts in the field. An important strength of the book is that many of the authors are, or have been, associated with the National Institutes of Health (NIH). In fact, the text is based on a course given at the NIH and headed by the book's editor, John I. Gallin. The authors are particularly knowledgeable about NIH guidelines and regulations that govern much of the clinical research conducted in the United States. The book also contains valuable sections on how to obtain funding from the NIH for clinical research and is particularly strong in the area of ethical, regulatory, and legal issues. Given the problems with clinical research protocols that have been sufficiently serious to close down entire universities in recent years, this book clearly fulfills an important function for anyone involved in clinical research. The book is up to date and includes chapters on women and minorities, telemedicine, and animal models of human diseases, each of which is well written and informative. However, one or more separate chapters on the unique issues associated with genetics, genomics, and gene therapy would have been an appropriate and important addition to this otherwise comprehensive book. The concise initial chapters on bioethics, institutional review boards (IRBs), and data and safety monitoring provide important information needed to prepare investigators for conducting clinical research, at least as judged by the questions on several of the examinations that the NIH and my own institution require for certification to conduct clinical research. Chapter 8 presents the instructive story of the development of, and problems with, the antiviral drug fialuridine, which was ultimately found to have mitochondrial toxicity. The story is a voyage through all of the institutional and societal regulators. It is also a personal account told by a scientist who was in the middle of a stressful and at times tragic story. This chapter, like all the others, is focused on educating the reader, rather than pushing a political agenda, an approach in keeping with the spirit of the book and its roots in the NIH course on clinical research. A useful chapter written by two employees of the Food and Drug Administration describes the critical functions of this government agency in the regulation of drugs and biologic products. Although one could criticize the editor for relying so heavily on insiders to write chapters in the book, I think this is actually a strength. There are certainly many controversial issues that cause tensions between clinical researchers and the federal agencies that oversee clinical research, but the point of this book is to provide a road map that investigators can use to navigate the complexities of regulations governing clinical research. Who better to draw this map than the regulators themselves? This book will be accessible to a wide range of readers. Seasoned clinical investigators will find it a useful reference and a valuable teaching tool. Beginning students and others who are involved in clinical research but who may not have had formal training in the field will find that this book provides an excellent introduction to the key issues all clinical investigators must be familiar with. The book contains an enormous amount of useful information, which is clearly presented. For example, the chapters on legal issues are explained in terms that can readily be understood by a physician or a nurse with no legal training. Brief chapters on statistical methods cover the high points that any clinical investigator needs to be comfortable with, including randomization, calculation of the sample size, hypothesis testing, and survival analysis. The discussions of small and large clinical trials are of course generic and limited to addressing the more obvious aspects of designing trials. These chapters are not likely to obviate the need for an experienced, well-trained principal investigator to serve as a mentor for such endeavors. The brief overviews of technology transfer, telemedicine, and animal models of human disease cover topics that are so complex that entire books could be written about them. Somewhat out of place is the chapter on how to prepare scientific images for publication and display. The chapter is too brief to provide sufficiently detailed information for those not already well versed in the use of these techniques and is too superficial to interest anyone who is already producing scientific images on desktop computers. This book is much needed and provides essentially all of the basic information required by investigators involved in clinical research, from both a practical perspective and a regulatory perspective. Although it will not take the place of more in-depth books in any of the many areas it touches on, there is very little information in this well-written and comprehensive book that all clinical investigators should not be familiar with. Given the appropriate increase in attention to regulations governing clinical research, this book will be an important resource for institutional libraries and IRBs. It is an excellent starting point for those embarking on a clinical research project, as well as a valuable reference that experienced investigators will probably want to have readily available. ...
Decision Making in Radiation Oncology: Volume 1
1 December 2010

Decision Making in Radiation Oncology: Volume 1
Decision Making in Radiation Oncology: Volume 1
548 pages | Dec 12, 2010 |ISBN:3642124623 | PDF | 8 Mb

Decision Making in Radiation Oncology is a reference book designed to enable radiation oncologists, including those in training, to make diagnostic and treatment decisions effectively and efficiently. The design is based on the belief that a picture is worth a thousand words. Knowledge is conveyed through an illustrative approach using algorithms, schemas, graphics, and tables. Detailed guidelines are provided for multidisciplinary cancer management and radiation therapy techniques. In addition to the attention-riveting algorithms for diagnosis and treatment
Oncology Clinical Trials: Successful Design, Conduct, and Analysis
26 September 2010

Oncology Clinical Trials: Successful Design, Conduct, and Analysis

Oncology Clinical Trials: Successful Design, Conduct, and Analysis by Kevin Kelly, Susan Halabi
Demos Medical Publishing | 2010 | ISBN: 1933864389 | 424 pages | PDF | 14 MB


Clinical trials are the engine of progress in the development of new drugs and devices for the detection, monitoring, prevention and treatment of cancer. A well conceived, carefully designed and efficiently conducted clinical trial can produce results that change clinical practice overnight, deliver new oncology drugs and diagnostics to the marketplace, and expand the horizon of contemporary thinking about cancer biology. A poorly done trial does little to advance the field or guide clinical practice, consumes precious clinical and financial resources and challenges the validity of the ethical contract between investigators and the volunteers who willingly give their time and effort to benefit future patients. With chapters written by oncologists, researchers, biostatisticians, clinical research administrators, and industry and FDA representatives,
Radiation Oncology: Management Decisions
30 September 2010

Radiation Oncology: Management Decisions

Radiation Oncology: Management Decisions
Publisher: Lippincott Williams & Wilkins; Second edition | ISBN : 0781732220 | December 2001 | 776 pages | PDF | 13.2MB

A concise and practical book for practicing radiation oncologists. Covers the salient points from the main Perez textbook. A short basic introduction to each site with anatomy,clinical symptoms, diagnostic work up, staging and treatment options. The radiation planning techniques are well outlined and practical. A must have for daily clinical practice - however not a replacement for the main Perez.
Principles and Practice of Gastrointestinal Oncology
22 December 2011

Principles and Practice of Gastrointestinal Oncology
Principles and Practice of Gastrointestinal Oncology
English | Lippincott Williams & Wilkins; Second edition | October 29, 2007 | ISBN-10: 0781776171 | 1008 pages | CHM | 51.4 Mb

Thoroughly updated for its Second Edition, this text provides comprehensive, interdisciplinary coverage of gastrointestinal cancer, including molecular biology, diagnosis, medical, surgical, and radiation therapy, and palliative care. The initial section, Principles of Gastrointestinal Oncology, includes an expanded radiation oncology chapter, an extensively revised cancer genetics chapter, and a completely rewritten medical oncology chapter emphasizing new agents. Subsequent sections focus on esophageal, gastric, pancreatic, hepatocellular, biliary tree, and colorectal cancer. Coverage of each anatomic site includes epidemiology, screening, and prevention; molecular biology and genetics; pathology; anatomy and staging; and clinical management. The final section on uncommon cancers includes new chapters on neuroendocrine tumors and small bowel cancers.
Leibel and Phillips Textbook of Radiation Oncology 3e
1 February 2011

Leibel and Phillips Textbook of Radiation Oncology 3e
Leibel and Phillips Textbook of Radiation Oncology 3e
CHM, 1664 pages, English (1416058974) | 89 Mb


Stay on top of the latest scientific and therapeutic advances with the new edition of Leibel and Phillips Textbook of Radiation Oncology. Dr. Theodore L. Phillips, in collaboration with two new authors, Drs. Richard Hoppe and Mack Roach, offers a multidisciplinary look at the presentation of uniform treatment philosophies for cancer patients emphasizing the "treat for cure" philosophy. You can also explore the implementation of new imaging techniques to locate and treat tumors, new molecularly targeted therapies, and new types of treatment delivery.
Clinical Radiation Oncology: Expert Consult
30 November 2011

Clinical Radiation Oncology: Expert Consult

Clinical Radiation Oncology: Expert Consult
Publisher: Sa und ers | 2011 | ISBN: 1437716377 | 1660 pages | PDF | 132 MB

Clinical Scenarios in Surgical Oncology (Clinical Scenarios in Surgery Series)
16 February 2011

Clinical Scenarios in Surgical Oncology (Clinical Scenarios in Surgery Series)

Clinical Scenarios in Surgical Oncology (Clinical Scenarios in Surgery Series)
560 pages | Dec 12, 2008 |ISBN:0781754666 | PDF | 67.5 Mb

This unique case-based review of surgical oncology offers excellent preparation for oral board examinations, which emphasize both general knowledge and case management. The book presents 91 cases structured to reflect the surgeon's decision-making process. Each case begins with a patient presentation and imaging studies or pathology results and proceeds through a series of decision points
Recent Trends in Radiation Chemistry
8 October 2010

Recent Trends in Radiation Chemistry


Recent Trends in Radiation Chemistry by James F. Wishart, BSM Rao


World Scientific Publishing Company | 2010 | ISBN: 9814282073 | 636 pages | PDF | 27 MB



Recent Trends in Radiation Chemistry is a state-of-the-art review of the present status and future trends in the field of radiation chemistry research. It covers a broad spectrum of topics, ranging from the historical perspective, instrumentation of accelerators in the nanosecond to femtosecond region, through the use of radiation chemical methods in the study of antioxidants and nanomaterials, radiation-induced DNA damage by ionizing radiation involving both direct and indirect effects, to ultrafast events in free electron transfer, radiation-induced processes at solid liquid interfaces and the recent work on infrared spectroscopy and radiation chemistry.