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Tumors of the Central Nervous System, Volume 4: Brain Tumors - Part 2
22 July 2012

Tumors of the Central Nervous System, Volume 4: Brain Tumors - Part 2

Tumors of the Central Nervous System, Volume 4: Brain Tumors - Part 2
2011 | ISBN: 9400717059 | PDF | 399 pages | 11 MB

This volume mainly contains information on the diagnosis, therapy, and prognosis of brain tumors. Insights on the understanding of molecular pathways involved in tumor biology are explained, which should lead to the development of effective drugs. Information on pathways (e.g., hedgehog) facilitates targeted therapies in cancer. Tumor models are also presented, which utilize expression data, pathway sensitivity, and genetic abnormalities, representing targets in cancer. For example, rat model of malignant brain tumors using implantation of doxorubicin with drug eluting beads for delivery is explained. The future of pathway-driven therapies for tumors is summarized. The importance of personalizing cancer care is emphasized. The need for supportive measures for survivors of brain cancer is pointed out, so is the quality of life monitoring. The need of rehabilitation therapy for patients with primary and metastatic brain tumors is also emphasized. Role of MicroRNA in distinguishing primary tumors from metastatic primary tumors is discussed. Advantages and limitations of chemotherapy (e.g., temozolomide and doxorubicin) are discussed. The complexity of tumor to tumor transfer is explained; examples discussed are: brain metastases from breast cancer and brain metastases fro non-small cell lung carcinoma. Identification and characterization of biomarkers, including those for metastatic brain tumors, are presented. Genomic analysis for identifying clinically relevant subtypes of glioblastoma is included. A large number of imaging modalities are detailed to study progression and invasion of gliomas.
Diagnostic Pathology of Ovarian Tumors
15 July 2012

Diagnostic Pathology of Ovarian Tumors

Diagnostic Pathology of Ovarian Tumors
2011 | ISBN: 1441997504 | PDF | 324 pages | 53.5 MB

Diagnostic Pathology of Ovarian Tumors offers a focus on the pathology of ovarian neoplasia with detailed clinically relevant information for practicing pathologists not found in other more general volumes of gynecologic pathology. This important work focuses almost entirely on strategies for accurate diagnosis and histologic subclassification, and the clinical correlates of these diagnoses. It provides evolving guidelines for detecting early ovarian cancer in prophylactic specimens; cutting-edge information on enhancing the reproducible and clinically meaningful subclassification of ovarian carcinoma as well as new proposals for ovarian carcinoma grading. Richly illustrated, containing abundant tables and figures as well as bulleted points of information, Diagnostic Pathology of Ovarian Tumors is the first text offering chapters written by practicing gynecologists on how clinical data can enhance pathologic diagnostic accuracy, how pathologists can efficiently convey their diagnostic opinions to gynecologists, and the way in which a given diagnosis triggers a cascade of clinical testing and therapy.
Atlas and Synopsis of Lever's Histopathology of the Skin - 2nd edition
22 July 2012

Atlas and Synopsis of Lever's Histopathology of the Skin - 2nd edition

Atlas and Synopsis of Lever's Histopathology of the Skin - 2nd edition
2006 | ISBN: 0781768454 | PDF | 512 pages | 46 MB

Based on Lever's Histopathology of the Skin, Ninth Edition, this full-color atlas presents an algorithmic pattern recognition approach to differential diagnosis of skin diseases. Whereas Lever's classifies diseases by pathogenesis, this atlas aids in differential diagnosis of unknown cases by classifying diseases morphologically, based on their location in the skin and the patterns and cell types seen through the microscope. Within each morphologic category, prototypic disorders are described and illustrated with full-color photomicrographs, and a list of differential diagnostic possibilities is presented. The atlas contains over 1,300 full-color illustrations.
Diagnostic, Prognostic and Therapeutic Value of Gene Signatures
22 April 2012

Diagnostic, Prognostic and Therapeutic Value of Gene Signatures

Diagnostic, Prognostic and Therapeutic Value of Gene Signatures

Gene expression studies have revealed diagnostic profiles and upregulation of specific pathways in many solid tumors. The explosion of new information in gene expression profiling could potentially lead to the development of tailored treatments in many solid tumors. In addition many studies are ongoing to validate these signatures also in predicting response to hormonal, chemotherapeutic and targeted agents in breast cancer as well as in other tumors.

Diagnostic, Prognostic and Therapeutic Value of Gene Signatures provides readers a useful and comprehensive resource about the range of applications of microarray technology in oncological diseases. Topics covered include gene signatures and soft tissue sarcomas, prognostic relevance of breast cancer signatures, gene expression profiling of colorectal cancer and liver metastasis, gene signatures in GISTs, CNVs and gene expression profiles in pancreatic cancer, and gene signatures in head/neck, lung and gastric tumors.

Diagnostic, Prognostic and Therapeutic Value of Gene Signatures will be of great value to residents and fellows, physicians, pathologists and medical oncologists.
Surgery of Spinal Tumors
20 April 2011

Surgery of Spinal Tumors


Surgery of Spinal Tumors by Jorg Klekamp, Madjid Samii,


S-r | 2007 | ISBN: 3540447148 | 544 pages | PDF | 35 MB


This comprehensive monograph describes the experience gained through the treatment of patients with spinal tumors over a 25-year period. It covers clinical presentations and neuroradiological features of intramedullary, extramedullary and extradural spinal tumors. Furthermore, it provides step-by-step intraoperative photographs to describe surgical strategies and techniques, and gives detailed statistical analyses on postoperative outcomes by focussing on postoperative complications as well as short-term and long-term results. A reliable reference, this book will be of great interest to neurosurgeons, neurologists, neuroradiologists, neuromolecular biologists, neurophysiotherapists and occupational therapists.
Mohs Surgery and Histopathology: Beyond the Fundamentals
26 March 2010

Mohs Surgery and Histopathology: Beyond the Fundamentals


Mohs Surgery and Histopathology: Beyond the Fundamentals
Cambridge University Press | English | 2009-06-08 | ISBN: 0521888042 | 200 pages | PDF | 21 MB

Introduction to Histopathology
22 August 2010

Introduction to Histopathology

Introduction to Histopathology
Publisher: MEDICINA PUBLISHING co. | English | PDF | SBN-10: 963242509X | 292 pages | 22.3MB
Levers Histopathology of the Skin (Tenth Editon)
10 March 2013


Levers Histopathology of the Skin (Tenth Editon)

Levers Histopathology of the Skin (Tenth Editon)
David E Elder
English | ISBN: 0781773636 | 2008-09-01 | PDF | 1408 pages | 39,6 Mb
Histopathology of Preclinical Toxicity Studies - Interpretation and Relevance in Drug Safety Evaluat...
9 November 2013


Histopathology of Preclinical Toxicity Studies - Interpretation and Relevance in Drug Safety Evaluat...

Histopathology of Preclinical Toxicity Studies - Interpretation and Relevance in Drug Safety Evaluation, 4 edition
Peter Greaves,
2012 | ISBN-10: 0444538569 | 892 pages | PDF | 55 MB

Malignant Liver Tumors: Current and Emerging Therapies
20 October 2010

Malignant Liver Tumors: Current and Emerging Therapies


Malignant Liver Tumors: Current and Emerging Therapies by Pierre-Alain Clavien, Stefan Breitenstein


Publisher: Wiley-Blackwell | 2010-02-15 | ISBN: 1405179767 | PDF | 576 pages | 15 MB



This comprehensive and critical review of current and established treatment modalities for malignant liver tumors is designed to help you sort through the proliferation of competitive approaches and choose the best treatment options for your patient. Dr. Clavien and his contributors consider all the options radiological, surgical, pharmaceutical, and emerging/novel therapies and help you find the best single or combined therapy.
Building on the success of the previous edition, this extremely thorough revision: